TETRAHYDROCORTISOL
Synonym(s):THF;Urocortisol;5β-Tetrahydrocortisol;Tetrahydro F;Tetrahydrocompound F
- CAS NO.：53-02-1
- Empirical Formula: C21H34O5
- Molecular Weight: 366.49
- MDL number: MFCD00067597
- EINECS: 200-159-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:50:14
What is TETRAHYDROCORTISOL?
The Uses of TETRAHYDROCORTISOL
Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.
What are the applications of Application
Tetrahydrocortisol is a metabolite of cortisol.
Definition
ChEBI: Tetrahydrocortisol is a 3alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a glucocorticoid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It derives from a hydride of a 5beta-pregnane.
Properties of TETRAHYDROCORTISOL
| Melting point: | −108 °C(lit.) |
| Boiling point: | 65-67 °C(lit.) |
| Density | 0.889 g/mL at 25 °C(lit.) |
| vapor density | 2.5 (vs air) |
| vapor pressure | 114 mm Hg ( 15 °C) |
| refractive index | n |
| Flash point: | 1 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Very Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Sligh |
| form | Solid |
| pka | 12.48±0.70(Predicted) |
| color | <10(APHA) |
| Stability: | Hygroscopic |
Safety information for TETRAHYDROCORTISOL
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for TETRAHYDROCORTISOL
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