TERT-BUTYLUREA
- CAS NO.：1118-12-3
- Empirical Formula: C5H12N2O
- Molecular Weight: 116.16
- MDL number: MFCD00025448
- EINECS: 214-257-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-31 14:38:37
What is TERT-BUTYLUREA?
Chemical properties
white crystals or crystalline powder
Production Methods
tert-Butylurea is produced by treating 1 mol urea with 2 mol of tert-butanol in the presence of 2 mol of concentrated sulfuric acid at 20–25 ℃ with ice cooling.
Purification Methods
Possible impurity is N,N'-di-tert-butyl urea which is quite insoluble in H2O. Recrystallise it from hot H2O, filter off insoluble material, and cool to 0o to -5o with stirring. Dry in vacuum at room temperature over KOH or H2SO4. If dried at higher temperatures, it sublimes slowly. It can be recrystallised from EtOH as long white needles or from 95% aqueous EtOH as plates. During melting point determination the bath temperature has to be raised rapidly as the urea sublimes slowly above 100o at 760mm. [Smith & Emerson Org Synth Coll Vol III 151 1955, Beilstein 4 IV 665.]
Properties of TERT-BUTYLUREA
| Melting point: | ~185 °C (dec.) |
| Boiling point: | 217.23°C (rough estimate) |
| Density | 1.0551 (rough estimate) |
| refractive index | 1.4432 (estimate) |
| pka | 14.37±0.46(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White |
| BRN | 1744501 |
| CAS DataBase Reference | 1118-12-3(CAS DataBase Reference) |
| EPA Substance Registry System | tert-Butylurea (1118-12-3) |
Safety information for TERT-BUTYLUREA
Computed Descriptors for TERT-BUTYLUREA
New Products
Cyclopentane-1,2-dione Isopropyl amine Hydrochloride 8-hydroxy-7-methoxy-2,6-dimethylisoquinolinium iodide 4-Chlorobutyronitrile (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid Amino-4-methoxyben-zeneacetic acid 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile 3-Aminophenylacetic acid 2-Bromo-5-iodopyridine Rifaximin EP Impurity-G N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
![1-(3,5-DIHYDROXYPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-ETHANONE, HYDROCHLORIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB2752536.gif)
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