3,5-Dibenzyloxyacetophenone
- CAS NO.:28924-21-2
- Empirical Formula: C22H20O3
- Molecular Weight: 332.39
- MDL number: MFCD00004777
- EINECS: 249-315-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:42
What is 3,5-Dibenzyloxyacetophenone?
Chemical properties
beige crystalline powder.
The Uses of 3,5-Dibenzyloxyacetophenone
3,5-Dibenzyloxyacetophenone is used in the synthesis of enantiomerically pure B-ring modified analogs of (-)-epicatechin gallate.
The Uses of 3,5-Dibenzyloxyacetophenone
The product 3,5-dibenzyloxyacetophenone is widely used as intermediate in the production of a pharmaceutical for treatment of obesity, diabetes, glaucoma, AIDS, HIV infection, antiinflammatory effects, and also in the treatment of disorders which result from leukotriene, tranquilizers, hypotensives, diuretics, and antiglaucoma agents.[1]
References
[1] Ganapati D. Yadav, Omprakash V. Badure. “Selective acylation of 1,3-dibenzyloxybenzene to 3,5-dibenzyloxyacetophenone over cesium modified dodecatungstophosphoric acid (DTP) on clay.” Applied Catalysis A: General 348 1 (2008): Pages 16-25.
Properties of 3,5-Dibenzyloxyacetophenone
| Melting point: | 60-62 °C (lit.) |
| Boiling point: | 429.52°C (rough estimate) |
| Density | 1.1079 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in dichloromethane, ethyl acetate and methanol |
| form | Solid |
| color | Off-White to Pale Yellow |
| CAS DataBase Reference | 28924-21-2(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]- (28924-21-2) |
Safety information for 3,5-Dibenzyloxyacetophenone
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,5-Dibenzyloxyacetophenone
| InChIKey | KOJXGMJOTRYLBD-UHFFFAOYSA-N |
3,5-Dibenzyloxyacetophenone manufacturer
Jaagruthi Lifesciences
Kavya Pharma
ASM Organics
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