tert-Butyl phenyl carbonate
- CAS NO.：6627-89-0
- Empirical Formula: C11H14O3
- Molecular Weight: 194.23
- MDL number: MFCD00008804
- EINECS: 229-601-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:25
What is tert-Butyl phenyl carbonate?
Chemical properties
Clear light yellow liquid
The Uses of tert-Butyl phenyl carbonate
tert-Butyl phenyl carbonate is used in determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography. It is also used in the synthesis of 2-nitroindoles and as a reagent for mono-Boc protection of α,ω-diamines.
What are the applications of Application
tert-Butyl phenyl carbonate is a reagent for mono-Boc protection of α,ω-diamines
Purification Methods
If IR is free from OH, then purify it by redistillation; otherwise dissolve it in Et2O, wash it with 5% HCl, then H2O, dry it (MgSO4), evaporate and distil it through a Claisen head under vacuum. Care should be taken as distillation of large quantities can lead to decomposition with liberation of CO2 and isobutylene; use the necessary precautions. [Carpino J Am Chem Soc 79 98 1957, Beilstein 6 IV 629.]
Properties of tert-Butyl phenyl carbonate
| Boiling point: | 83 °C/0.6 mmHg (lit.) |
| Density | 1.05 g/mL at 20 °C (lit.) |
| refractive index | n |
| Flash point: | 214 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Liquid or Low Melting Solid |
| color | Colorless |
| Water Solubility | Slightly soluble in water. |
| BRN | 2361602 |
| NIST Chemistry Reference | Carbonic acid 1,1-dimethylethyl ester(6627-89-0) |
Safety information for tert-Butyl phenyl carbonate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for tert-Butyl phenyl carbonate
New Products
8-Bromo-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane Maleic hydrazide 4-FLUOROBENZOYLACETONITRILE 3,4-Dihydroxyacetophenone 3,4-Dimethoxyacetophenone 4-Nitroacetophenone DL-Glutamic acid 3-Nitroacetophenone 4'-Chloro-3'-nitroacetophenone 3-Hydroxy-2-methylbenzoic acid 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 3-acetyl pyridine 4-FORMYL-N-CBZ-PIPERIDINE 2-pyridineacetonitrile 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Trenbolone acetate 4-Bromobenzaldehyde 4-bromo-2-ethyl-3-fluorobenzoic acid 6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 2-Chlorophenyl diphenyl chloromethaneRelated products of tetrahydrofuran
You may like
-
tert-Butyl phenyl carbonate CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl Phenyl Carbonate CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl phenyl carbonate 98% (GC) CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl phenyl carbonate CAS 6627-89-0View Details
6627-89-0 -
586-37-8 98+View Details
586-37-8 -
1-Boc-Azetidine-3-yl-methanol 98+View Details
142253-56-3 -
4-Acetylbiphenyl 92-91-1 98+View Details
92-91-1 -
99-93-4 98+View Details
99-93-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.