tert-Butyl phenyl carbonate
- CAS NO.：6627-89-0
- Empirical Formula: C11H14O3
- Molecular Weight: 194.23
- MDL number: MFCD00008804
- EINECS: 229-601-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:10:33
What is tert-Butyl phenyl carbonate?
Chemical properties
Clear light yellow liquid
The Uses of tert-Butyl phenyl carbonate
tert-Butyl phenyl carbonate is used in determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography. It is also used in the synthesis of 2-nitroindoles and as a reagent for mono-Boc protection of α,ω-diamines.
What are the applications of Application
tert-Butyl phenyl carbonate is a reagent for mono-Boc protection of α,ω-diamines
Purification Methods
If IR is free from OH, then purify it by redistillation; otherwise dissolve it in Et2O, wash it with 5% HCl, then H2O, dry it (MgSO4), evaporate and distil it through a Claisen head under vacuum. Care should be taken as distillation of large quantities can lead to decomposition with liberation of CO2 and isobutylene; use the necessary precautions. [Carpino J Am Chem Soc 79 98 1957, Beilstein 6 IV 629.]
Properties of tert-Butyl phenyl carbonate
| Boiling point: | 83 °C/0.6 mmHg (lit.) |
| Density | 1.05 g/mL at 20 °C (lit.) |
| refractive index | n |
| Flash point: | 214 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Liquid or Low Melting Solid |
| color | Colorless |
| Water Solubility | Slightly soluble in water. |
| BRN | 2361602 |
| NIST Chemistry Reference | Carbonic acid 1,1-dimethylethyl ester(6627-89-0) |
Safety information for tert-Butyl phenyl carbonate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for tert-Butyl phenyl carbonate
New Products
Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
tert-Butyl phenyl carbonate CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl Phenyl Carbonate CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl phenyl carbonate 98% (GC) CAS 6627-89-0View Details
6627-89-0 -
tert-Butyl phenyl carbonate CAS 6627-89-0View Details
6627-89-0 -
7292-71-9 AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 98+View Details
7292-71-9 -
84145-28-8 98+View Details
84145-28-8 -
2-(2-Chlorophenyl)glycine 98+View Details
88744-36-9 -
8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione 39124-19-1 98+View Details
39124-19-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.