tert-Butyl 2,2,2-trichloroacetimidate

Synonym(s):TBTA

CAS NO.：98946-18-0
Empirical Formula: C6H10Cl3NO
Molecular Weight: 218.51
MDL number: MFCD00077410
EINECS: 629-631-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:20:38

tert-Butyl 2,2,2-trichloroacetimidate Structural

What is tert-Butyl 2,2,2-trichloroacetimidate?

Chemical properties

Clear colorless to pale yellow liquid

The Uses of tert-Butyl 2,2,2-trichloroacetimidate

tert-Butyl 2,2,2-trichloroacetimidate is used to produce di-tert-butyl peroxide at temperature of -5°C. It may be used in the synthesis of N-α-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-serine, caged building block. It may be used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.

Properties of tert-Butyl 2,2,2-trichloroacetimidate

Melting point:	21 °C(lit.)
Boiling point:	65 °C11 mm Hg(lit.)
Density	1.222
refractive index	n20/D 1.456(lit.)
Flash point:	131 °F
storage temp.	2-8°C
solubility	Soluble in organic solvents, cyclo hexane.
form	Liquid or Low Melting Crystalline Mass
pka	2.49±0.70(Predicted)
Specific Gravity	1.222
color	Clear colorless to pale yellow
Sensitive	Moisture Sensitive
BRN	1770049
Stability:	Hygroscopic
CAS DataBase Reference	98946-18-0(CAS DataBase Reference)

Safety information for tert-Butyl 2,2,2-trichloroacetimidate

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.