tert-Butyl 2-(aminomethyl)phenylcarbamate
Synonym(s):(2-Aminomethyl-phenyl)-carbamic acid tert-butyl ester;tert-Butyl N-(2-aminomethylphenyl)carbamate
- CAS NO.：849020-94-6
- Empirical Formula: C12H18N2O2
- Molecular Weight: 222.28
- MDL number: MFCD04037902
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:02:51
What is tert-Butyl 2-(aminomethyl)phenylcarbamate?
The Uses of tert-Butyl 2-(aminomethyl)phenylcarbamate
Tert-Butyl 2-(aminomethyl)phenylcarbamate can be used as reactant for Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize)
The Uses of tert-Butyl 2-(aminomethyl)phenylcarbamate
Reactant for:
- Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategy
- Preparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclization
- Preparation of pyrazinone inhibitors of mast cell tryptase
Properties of tert-Butyl 2-(aminomethyl)phenylcarbamate
| Boiling point: | 238-242℃ |
| Density | 1.054g/mLat 25℃ |
| Flash point: | 71°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 13.67±0.70(Predicted) |
Safety information for tert-Butyl 2-(aminomethyl)phenylcarbamate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for tert-Butyl 2-(aminomethyl)phenylcarbamate
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