TC-2559 difumarate
- CAS NO.：2454492-41-0
- Empirical Formula: C16H22N2O5
- Molecular Weight: 322.36
- Update Date: 2026-04-24 14:58:07
What is TC-2559 difumarate?
Biological Activity
TC 2559 difumarate is a subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes respectively). Displays selectivity for (α4)2(β2)3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task.
Storage
Desiccate at RT
Properties of TC-2559 difumarate
| Water Solubility | Soluble to 100 mM in water |
Safety information for TC-2559 difumarate
Computed Descriptors for TC-2559 difumarate
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