TAPSO
Synonym(s):2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid;N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid
- CAS NO.：68399-81-5
- Empirical Formula: C7H17NO7S
- Molecular Weight: 259.28
- MDL number: MFCD00038352
- EINECS: 269-993-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:43:29
What is TAPSO?
Chemical properties
white powder
The Uses of TAPSO
TAPSO is a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.
What are the applications of Application
TAPSO Free Acid is a biological buffer (zwitterionic) useful in cell culture media formulations
References
[1] Gupta B, et al. Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions. Journal of Solution Chemistry, 2013; 42: 2296–2309.
[2] Gupta ;B, et al. Interactions of bovine serum albumin with biological buffers, TES, TAPS, and TAPSO in aqueous solutions. Process Biochemistry, 2013; 48: 1686-1696.
[3] Taha M, et al. New Insights into Buffer-Ionic Salt Interactions: Solubilities, Transfer Gibbs Energies, and Transfer Molar Volumes of TAPS and TAPSO from Water to Aqueous Electrolyte Solutions. Journal of Solution Chemistry, 2010; 39:1665–1680.
Properties of TAPSO
| Melting point: | 224-229 °C (dec.) |
| Density | 1.07607 g/cm3(Temp: 25.00 °C) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Powder |
| color | Off-white to yellow |
| pka | 7.6(at 25℃) |
| PH Range | 7.0 - 8.2 |
| Water Solubility | soluble |
| Merck | 13,9148 |
| BRN | 2113949 |
| InChI | InChI=1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15) |
| CAS DataBase Reference | 68399-81-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (68399-81-5) |
Safety information for TAPSO
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TAPSO
| InChIKey | RZQXOGQSPBYUKH-UHFFFAOYSA-N |
| SMILES | C(S(O)(=O)=O)C(O)CNC(CO)(CO)CO |
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