TAPI-1
Synonym(s):N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt
- CAS NO.：163847-77-6
- Empirical Formula: C26H37N5O5
- Molecular Weight: 499.6
- MDL number: MFCD02684280
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-15 16:23:17
What is TAPI-1?
The Uses of TAPI-1
TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor.
Biochem/physiol Actions
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).
Storage
Store at -20°C
Properties of TAPI-1
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka | 9.17±0.20(Predicted) |
| form | powder |
| color | white to beige |
Safety information for TAPI-1
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for TAPI-1
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