SQ 109

Synonym(s):N-[(2E)-3,7-Dimethyl-2,6-octadienyl]-N′-tricyclo[3.3.1.13,7]dec-2-yl-1,2-ethanediamine;N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N??-tricyclo[3.3.1.13,7]dec-2-yl-1,2-ethanediamine;NSC 722041

SQ109 has been used:

as an antitubercular?agent to study its interactions with mycobacterial membrane proteins large 3 (MmpL3) binding pocket
as a positive control to determine the minimum inhibitory concentration (MIC) of ohmyungsamycins (OMS) A and B against Mycobacterium tuberculosis?(Mtb) using the resazurin microtiter assay (REMA) plate method
as an inhibitor of MmpL3 to explore the utility of mycobacterial CRISPR interference for validating target gene essentiality and compound mode of action

SQ109 is a 1,2-ethylenediamine, which is related to ethambutol.

SQ109 exhibits activity against Helicobacter pylori and the fungi Candida albicans. It might also possess anti-bacterial activity.

Boiling point:	450.0±33.0 °C(Predicted)
Density	0.97±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka	9.80±0.20(Predicted)
form	oil
color	colorless to yellow

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.