SP-420
- CAS NO.：911714-45-9
- Empirical Formula: C16H21NO6S
- Molecular Weight: 355.41
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:57
What is SP-420?
Description
SP 420 is an iron chelator and a derivative of desferrothiocin. It induces iron excretion in rat bile and urine with an iron-clearing efficiency (ICE) value of 26.7% when administered at a dose of 300 μmol/kg and decreases iron levels in rat liver and heart at 384 μmol/kg per day. SP 420 (75 μmol/kg) also induces iron excretion in iron-overloaded C. apella monkeys (ICE = 26.3%).
Properties of SP-420
| Melting point: | 82-83℃ (ethyl acetate hexane ) |
| Boiling point: | 562.2±60.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10mg/mL; DMSO: 15mg/mL; Ethanol: 15mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2mg/mL |
| form | A crystalline solid |
| pka | 1.02±0.40(Predicted) |
| color | Light yellow to khaki |
Safety information for SP-420
Computed Descriptors for SP-420
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