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HomeProduct name listsimfibrate

simfibrate

  • CAS NO.:14929-11-4
  • Empirical Formula: C23H26Cl2O6
  • Molecular Weight: 469.35
  • MDL number: MFCD00865760
  • EINECS: 2389987
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2026-01-05 11:31:08
simfibrate Structural

What is simfibrate?

Originator

Cholesorbin,Takeda,Japan,1971

Definition

ChEBI: Simfibrate is an organic molecular entity.

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

Properties of simfibrate

Melting point: 51-53°
Boiling point: bp0.03 197-200°; bp0.15 220-230°
Density  1.2623 (estimate)

Safety information for simfibrate

Computed Descriptors for simfibrate

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