SGC-GAK-1N
Synonym(s):CA71;CA93 Negative Control;N-Methyl-6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;SGC-GAK-1 Negative Control
- CAS NO.：2226517-74-2
- Empirical Formula: C20H19F3N2O3
- Molecular Weight: 392.37
- Update Date: 2026-01-13 11:20:46
What is SGC-GAK-1N?
Biochem/physiol Actions
SGC-GAK-1N (CA71) is a structure analog of and the recommended negative control for the ATP-competitive cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 (CA93) (GAK KD = 1.9 nM/SGC-GAK-1 vs. 7.1 μM/SGC-GAK-1N by ligand competitive binding assay; GAK IC50 = 110 nM/SGC-GAK-1 vs. >50 μM/SGC-GAK-1N by cellular target engagement assay; Dengue viral entry and packaging IC50 = 920 nM/SGC-GAK-1 vs. >10 μM/SGC-GAK-1N). For characterization details of the active probe, SGC-GAK-1, please visit the SGC-GAK-1 probe summary on the Structural Genomics Consortium (SGC) website.SGC-GAK-1, the active probe, is available from Sigma. To learn more about and purchase SGC-GAK-1, click here.To learn about other SGC chemical probes, visit sigma.com/sgc
Properties of SGC-GAK-1N
| storage temp. | 2-8°C |
| form | powder |
| color | dark green to black |
Safety information for SGC-GAK-1N
Computed Descriptors for SGC-GAK-1N
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