SB 222200
Synonym(s):(S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide
- CAS NO.：174635-69-9
- Empirical Formula: C26H24N2O
- Molecular Weight: 380.48
- MDL number: MFCD00944072
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-18 07:23:31
What is SB 222200?
The Uses of SB 222200
3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2).
What are the applications of Application
SB 222200 is a potent, selective non-peptide NK3 antagonist
Definition
ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.
Biological Activity
Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo .
Storage
Store at RT
Properties of SB 222200
| Melting point: | 154℃ |
| Boiling point: | 553.5±50.0 °C(Predicted) |
| Density | 1.142 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ~28 mg/mL, soluble |
| form | solid |
| pka | 12.88±0.46(Predicted) |
| color | light yellow |
Safety information for SB 222200
Computed Descriptors for SB 222200
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![SB 222200, [3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB6438432.gif)
You may like
-
SB 222200 CAS 174635-69-9View Details
174635-69-9 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details -
DGO36View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.