SB 222200
Synonym(s):(S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide
- CAS NO.：174635-69-9
- Empirical Formula: C26H24N2O
- Molecular Weight: 380.48
- MDL number: MFCD00944072
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:27
What is SB 222200?
The Uses of SB 222200
3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2).
What are the applications of Application
SB 222200 is a potent, selective non-peptide NK3 antagonist
Definition
ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.
Biological Activity
Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo .
Storage
Store at RT
Properties of SB 222200
| Melting point: | 154℃ |
| Boiling point: | 553.5±50.0 °C(Predicted) |
| Density | 1.142 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ~28 mg/mL, soluble |
| form | solid |
| pka | 12.88±0.46(Predicted) |
| color | light yellow |
Safety information for SB 222200
Computed Descriptors for SB 222200
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
![SB 222200, [3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB6438432.gif)
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