SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.：160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:09
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 14.28±0.20(Predicted) |
| color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4,4-Diethoxybutanenitrile 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Aminobenzo[d]thiazol-4-ol 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acid N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide 2-(difluoromethyl)-4H-chromen-4-oneRelated products of tetrahydrofuran
![THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER](https://img.chemicalbook.in/CAS/GIF/21344-30-9.gif)
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