SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.：160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:04
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 14.28±0.20(Predicted) |
| color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
Cyclopropane-1,1-dicarboxylic acid Cyclopentane-1,2-dione 2-Bromo-5-iodopyridine 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Amino-4-methoxyben-zeneacetic acid 3-Aminophenylacetic acid 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 3-Hydroxypropionitrile valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 4-Bromo Benzylcyanide 5-azidovalericacid 4-bromo-1H-pyrazole-3-carboxylic acid Isopropyl amine Hydrochloride tert-butyl 4-(6-(8-cyclopentyl-5-methyl-7-oxo-6-vinyl-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)pyridin-3-yl)piperazine-1-carboxylateRelated products of tetrahydrofuran
![THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER](https://img.chemicalbook.in/CAS/GIF/21344-30-9.gif)
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