SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.：160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:09
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 14.28±0.20(Predicted) |
| color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 4-Nitrobenzotrifluoride 2-Pentyn-1-oLRelated products of tetrahydrofuran
![THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER](https://img.chemicalbook.in/CAS/GIF/21344-30-9.gif)
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