(SAR9,MET(O2)11)-SUBSTANCE P
Synonym(s):Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2
- CAS NO.：110880-55-2
- Empirical Formula: C64H100N18O15S
- Molecular Weight: 1393.66
- MDL number: MFCD00076787
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-22 15:57:46
What is (SAR9,MET(O2)11)-SUBSTANCE P?
The Uses of (SAR9,MET(O2)11)-SUBSTANCE P
[Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4).
What are the applications of Application
[Sar-9, Met(O2)-11]-Substance P is a selective NK1 receptor agonist
Biochem/physiol Actions
Highly selective NK-1 receptor agonist.
Storage
Store at -20°C
Properties of (SAR9,MET(O2)11)-SUBSTANCE P
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O : 50 mg/mL (35.88 mM; Need ultrasonic) |
| pka | 13.31±0.20(Predicted) |
| form | Lyophilized solid. |
| color | White to off-white |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for (SAR9,MET(O2)11)-SUBSTANCE P
Computed Descriptors for (SAR9,MET(O2)11)-SUBSTANCE P
New Products
2-Bromo-4-hydroxypyridine Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 2'-Fluoroacetophenone 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID N-Methyl-2-amino-2-methylpropionamide 4-(FMOC-AMINO)-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe 2,5 Dibromopyridine Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![SUBSTANCE P, (9-SAR, 11-MET(O2)), [2-PROLYL-3,4-3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB5429338.gif)
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