Sacubitril Impurity 7
- CAS NO.：149709-44-4
- Empirical Formula: C22H25NO5
- Molecular Weight: 383.44
- MDL number: MFCD00921225
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 11:24:09
What is Sacubitril Impurity 7?
The Uses of Sacubitril Impurity 7
Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
Properties of Sacubitril Impurity 7
| Boiling point: | 705.4±60.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM) DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM) Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM) |
| form | A crystalline solid |
| pka | 4.59±0.23(Predicted) |
| color | White to off-white |
Safety information for Sacubitril Impurity 7
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Sacubitril Impurity 7
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
Sacubitril Diacid Impurity 98%View Details
149709-44-4 -
SACUBITRILAT 149709-44-4 90 % AboveView Details
149709-44-4 -
(2R,4S)-4-[(3-CARBOXY-1-OXOPROPYL)AMINO]-4-[(P- PHENYLPHENYL)METHYL]-2-METHYLBUTANOIC ACID 149709-44-4 90 % AboveView Details
149709-44-4 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO29View Details -
DGO32View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.