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sabadine

sabadine Structural

What is sabadine?

Description

This alkaloid was isolated by Merck from the seeds of Schoenocaulon officinale. A. Gray. It crystallizes from Et20 in colourless needles and forms crystalline salts, e.g. the hydrochloride as the dihydrate, m.p. 282-4°C (dry, dec.); nitrate which is sparingly soluble in H20 and the aurichloride which forms goldenyellow needles.

References

Merck., Chern. Soc. Abstr., 60,844 (1891)

Properties of sabadine

Melting point: 256-258° (dec)
Boiling point: 614.28°C (rough estimate)
alpha  D25 -11° (c = 1.93 in alc)
Density  1.1622 (rough estimate)
refractive index  1.6290 (estimate)
pka 13.19±0.70(Predicted)
EPA Substance Registry System Cevane-3,4,12,14,16,17,20-heptol, 3-acetate, (3.beta.,4.alpha.,16-.beta.)- (124-80-1)

Safety information for sabadine

Computed Descriptors for sabadine

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