S(-)-VERAPAMIL
- CAS NO.：36622-28-3
- Empirical Formula: C27H38N2O4
- Molecular Weight: 454.6
- MDL number: MFCD00869809
- EINECS: 253-132-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 22:16:43
What is S(-)-VERAPAMIL?
Chemical properties
White Solid
The Uses of S(-)-VERAPAMIL
Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.
Definition
ChEBI: (S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.
Biochem/physiol Actions
Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.
Properties of S(-)-VERAPAMIL
| Melting point: | 131-133 °C |
| solubility | H2O: >30 mg/mL |
| form | solid |
| color | white |
| optical activity | [α]22/D 6.1°, c = 0.1 in ethanol(lit.) |
Safety information for S(-)-VERAPAMIL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for S(-)-VERAPAMIL
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
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