S-Methyl-L-cysteine
Synonym(s):(R)-2-Amino-3-(methylmercapto)propionic acid;SMLC
- CAS NO.：1187-84-4
- Empirical Formula: C4H9NO2S
- Molecular Weight: 135.18
- MDL number: MFCD00002612
- EINECS: 214-701-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is S-Methyl-L-cysteine?
Chemical properties
white to light beige fine crystalline powder
The Uses of S-Methyl-L-cysteine
S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). It has been studied as a theurapeutic for neurodegenerative diseases including Parkinson′s.
What are the applications of Application
S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by MSRA
Definition
ChEBI: A cysteine derivative that is L-cysteine in which the hydrogen attached to the sulfur is replaced by a methyl group.
Purification Methods
Likely impurities are cysteine and S-methyl-dl-cysteine. Crystallise it from H2O by adding 4volumes of EtOH. It also crystallises from MeOH with m 234-236o(dec), but after sublimation i t has m 267-270o and [] 27D -31.6o (c 1, H2O). [Rinderknecht et al. Helv Chim Acta 41 1, 10 1958, Theodoropoulos Acta Chem Scand 13 383 1959, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1904 1961, Beilstein 4 IV 3145.]
Properties of S-Methyl-L-cysteine
| Melting point: | ~240 °C (dec.) |
| Boiling point: | 300.3±37.0 °C(Predicted) |
| alpha | -29.5 º (c=1,water) |
| Density | 1.149 (estimate) |
| refractive index | -30 ° (C=2, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Aqueous Acid (Slightly, Sonicated), Aqueous Base (Sparingly, Sonicated), Water ( |
| form | Solid |
| pka | pK1:8.97 (25°C) |
| color | White to Off-White |
| BRN | 1721675 |
| CAS DataBase Reference | 1187-84-4(CAS DataBase Reference) |
| NIST Chemistry Reference | s-Methyl-L-cysteine(1187-84-4) |
Safety information for S-Methyl-L-cysteine
Computed Descriptors for S-Methyl-L-cysteine
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran
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