(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
- CAS NO.：78508-96-0
- Empirical Formula: C5H6O3
- Molecular Weight: 114.1
- MDL number: MFCD00075370
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:53:33
What is (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE?
Chemical properties
white to light yellow crystal powde
The Uses of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
(S)-(-)-5-Hydroxymethyl-2(5H)-furanone is used in the preparation of partially saturated heterocycles via a diastereoselective ring chain formation. It is also used in the synthesis of (1R,3S)-cis-chrysanthemic acid.
The Uses of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
(S)-(?)-5-Hydroxymethyl-2(5H)-furanone can be used as a starting material in the preparation of:
- Partially saturated heterocycles via a diastereoselective ring chain formation.
- A natural product named (+)-muscarine.
- 3′-Ethynylthymidine as a possible antiviral agent.
Properties of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
| Melting point: | 41-43 °C(lit.) |
| Boiling point: | 173.58°C (rough estimate) |
| Density | 1.2583 (rough estimate) |
| refractive index | 1.4630 (estimate) |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly), Water (Sparingly) |
| form | Solid |
| pka | 13.51±0.10(Predicted) |
| color | Off-White Low-Melting |
| optical activity | [α]20/D 144°, c = 1 in H2O |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Hygroscopic |
| BRN | 3537455 |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 78508-96-0(CAS DataBase Reference) |
Safety information for (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
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