(S)-(+)-Glycidyl Phthalimide
Synonym(s):(S)-N-Glycidylphthalimide
- CAS NO.：161596-47-0
- Empirical Formula: C11H9NO3
- Molecular Weight: 203.19
- MDL number: MFCD04973350
- EINECS: 454-720-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-20 10:32:07
What is (S)-(+)-Glycidyl Phthalimide?
Chemical properties
White powder
The Uses of (S)-(+)-Glycidyl Phthalimide
N-(S)-Glycidylphthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500).
Synthesis
Phthalimide and (S)-1-substituent propylene oxide are used as raw materials, a reaction occurs under the action of a catalyst to generate 2-((S)-3-substituent-2-hydroxypropyl isodihydroindole-1,3-dione, and finally (S)-glycidyl phthalimide is generated by means of a ring-closure reaction.
Preperation
Phthalimide and (S)-1-substituent propylene oxide are used as raw materials, and a reaction occurs under the action of a catalyst to generate 2-((S)-3-substituent-2-hydroxypropyl isodihydroindole-1,3-dione, and finally (S)-glycidyl phthalimide is generated using a ring-closure reaction.
Properties of (S)-(+)-Glycidyl Phthalimide
| Melting point: | 102 °C |
| Boiling point: | 347.4±15.0 °C(Predicted) |
| Density | 1.446±0.06 g/cm3(Predicted) |
| vapor pressure | 0.001-2.17Pa at 25-90.25℃ |
| refractive index | 10 ° (C=2.2, CHCl3) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | -2.24±0.20(Predicted) |
| form | Solid |
| color | White |
Safety information for (S)-(+)-Glycidyl Phthalimide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Health Hazard GHS08 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for (S)-(+)-Glycidyl Phthalimide
(S)-(+)-Glycidyl Phthalimide manufacturer
Mekanar Pharma Private Limited
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Phone:+91-9948050784
Whatsapp: +91- 9948050784
product: 161596-47-0 99%
TIKVAH PHARMA SOLUTIONS PVT LTD
1Y
Phone:+91-7416400830
Whatsapp: +91-8341143995
product: 161596-47-0 99%
SRINI PHARMACEUTICALS PVT LTD
1Y
Phone:+91-7093200121
Whatsapp: +91-7093200121
product: 161596-47-0 98%
Kevy's Labs
Hyderabad
Phone:91-9000001018
Whatsapp: 91-9000001018
product: (2S)-2-Oxiranylmethyl-isoindole-1,3-dione
Arown Pharma
Hyderabad
Phone:91-8309108338
Whatsapp: 91-8309108338
product: (2S)-2-Oxiranylmethyl-isoindole-1,3-dione
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