(S)-AMPA

The Uses of (S)-AMPA

(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.

The Uses of (S)-AMPA

Active enantiomer of AMPA that induces apoptosis in cortical neurons

The Uses of (S)-AMPA

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.

What are the applications of Application

(S)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid is an active isomer of AMPA with no NMDAR activity

General Description

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

Biological Activity

Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .

Biochem/physiol Actions

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

Storage

Room temperature