(S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER
Synonym(s):(S)-α,α-Diphenylprolinol trimethylsilyl ether;(S)-α,α-Diphenylprolinol trimethylsilyl ether, 0.05M solution in toluene;(S)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine;(S)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine, 0.05M solution in toluene;(2S)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine
- CAS NO.:848821-58-9
- Empirical Formula: C20H27NOSi
- Molecular Weight: 325.52
- MDL number: MFCD08690083
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:03
What is (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER?
Chemical properties
Light yellow liquid
The Uses of (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER
Organocatalyst for 3-component reactions, and Robinson annulation of α,β-unsaturated aldehydes.
Properties of (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER
| Boiling point: | 412.7±35.0 °C(Predicted) |
| Density | 1.0459 g/mL at 25 °C |
| refractive index | n20/D 1.5513 |
| Flash point: | 110 °C |
| storage temp. | 2-8°C |
| form | liquid |
| pka | 10.01±0.10(Predicted) |
| color | yellow viscous |
| optical activity | [α]22/D -50°, c = 1 in chloroform |
| λmax | 193nm(lit.) |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
Safety information for (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
![Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-](https://img.chemicalbook.in/CAS/GIF/943757-71-9.gif)
![Pyrrolidine, 2-[bis(3,5-dimethylphenyl)[(trimethylsilyl)oxy]methyl]-, (2S)-](https://img.chemicalbook.in/CAS/GIF/848821-60-3.gif)
![(S)-(-)-2-[Bis(3,5-dimethylphenyl)hydroxymethyl]pyrrolidine](https://img.chemicalbook.in/CAS/GIF/131180-63-7.gif)
![S-2-[diphenyl[(triethylsilyl)oxy]Methyl]-Pyrrolidine](https://img.chemicalbook.in/CAS/GIF/864466-70-6.gif)
![S-2-[bis[3,5-bis(trifluoroMethyl)phenyl][[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-Pyrrolidine](https://img.chemicalbook.in/CAS/GIF/913699-13-5.gif)
![S-2-[bis[3,5-bis(3,5-diMethylphenyl]
[(triethylsilyl)oxy]Methyl]-Pyrrolidine](https://img.chemicalbook.in/CAS/20180808/GIF/1402544-73-3.gif)
![(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine](https://img.chemicalbook.in/CAS/GIF/848821-76-1.gif)
![(S)-[(diphenyl)-t-butyldimethylsiloxymethyl]pyrrolidine](https://img.chemicalbook.in/CAS/GIF/864466-71-7.gif)
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