S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
Synonym(s):2-(Acetylthio)succinic anhydride;SAMSA
- CAS NO.：6953-60-2
- Empirical Formula: C6H6O4S
- Molecular Weight: 174.17
- MDL number: MFCD00005526
- EINECS: 230-135-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 13:16:46
What is S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE?
General Description
S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.
Properties of S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
| Melting point: | 83-86 °C (lit.) |
| Boiling point: | 354.3±31.0 °C(Predicted) |
| Density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 6953-60-2(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanethioic acid, S-(tetrahydro-2,5-dioxo-3-furanyl) ester (6953-60-2) |
Safety information for S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
New Products
Cyclopentane-1,2-dione Isopropyl amine Hydrochloride 2-Bromo-5-iodopyridine 3-Aminophenylacetic acid Amino-4-methoxyben-zeneacetic acid 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-(3-aminopropylamino)ethanol 4-cyano 3-(trifluoromethyl)-n-(2,3-epoxy-2-methylpropionyl)aniline N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide 4-(5-(bis-(2-hydroxy ethyl)amino)-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 2-(3-amino propyl amino) ethyl bromide di hydrobromide 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide valeronitrileRelated products of tetrahydrofuran
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