(S)-3,4-DCPG
- CAS NO.：201730-11-2
- Empirical Formula: C10H9NO6
- Molecular Weight: 239.18
- MDL number: MFCD03453633
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 15:21:26
What is (S)-3,4-DCPG?
The Uses of (S)-3,4-DCPG
(S)-3,4-DCPG is a potent and selective mGluR-8a agonist.
What are the applications of Application
(S)-3,4-DCPG is a potent and selective mGluR-8a agonist
Biological Activity
Potent, selective mGlu 8a agonist (EC 50 = 31 nM). Displays > 100-fold selectivity over mGlu 1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo . Also potent anticonvulsant in mice in vivo .
Storage
Desiccate at RT
Properties of (S)-3,4-DCPG
| Boiling point: | 531.0±50.0 °C(Predicted) |
| Density | 1.634±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 33 mg/ml; PBS (pH 7.2): 10 mg/ml |
| pka | 1.59±0.10(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble to 100 mM in water |
| InChI | InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1 |
Safety information for (S)-3,4-DCPG
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P363:Wash contaminated clothing before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P501:Dispose of contents/container to..… |
Computed Descriptors for (S)-3,4-DCPG
| InChIKey | IJVMOGKBEVRBPP-ZETCQYMHSA-N |
| SMILES | C1(C(O)=O)=CC=C([C@H](N)C(O)=O)C=C1C(O)=O |
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