(S)-3-Fluoro-pyrrolidine hydrochloride
- CAS NO.:136725-53-6
- Empirical Formula: C4H9ClFN
- Molecular Weight: 125.57
- MDL number: MFCD04038718
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:53
What is (S)-3-Fluoro-pyrrolidine hydrochloride?
Chemical properties
Light pink to purple solid
The Uses of (S)-3-Fluoro-pyrrolidine hydrochloride
The derived amide acts as an inhibitor of dipeptidyl peptidase IV.1
The Uses of (S)-3-Fluoro-pyrrolidine hydrochloride
(S)-(+)-3-Fluoropyrrolidine, HCl
The Uses of (S)-3-Fluoro-pyrrolidine hydrochloride
(S)-(+)-3-Fluoropyrrolidine hydrochloride can be employed as a building block for the preparation of:
- Fluorinated pyrrolidine derivatives of cyclohexylglycine amides as potential inhibitors for dipeptidyl peptidase IV.
- Fluoropyrrolidine contaning N--ethylurea pyrazole derivatives as potential and selective inhibitors for Trypanosoma brucei and Trypanosoma cruzi parasitic causative agents.
- Urea derivatives of (S)-2-(3,4-difluorophenyl)-5-(3-fluoro-N-pyrrolidylamido)benzothiazole as potent antitrypanosomal agents.
Properties of (S)-3-Fluoro-pyrrolidine hydrochloride
| Melting point: | 183-187 °C(lit.) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Powder or Crystalline Powder |
| color | White to pale brown |
| optical activity | [α]20/D +8°, c = 1% in methanol |
| CAS DataBase Reference | 136725-53-6(CAS DataBase Reference) |
Safety information for (S)-3-Fluoro-pyrrolidine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-3-Fluoro-pyrrolidine hydrochloride
| InChIKey | LENYOXXELREKGZ-WCCKRBBISA-N |
(S)-3-Fluoro-pyrrolidine hydrochloride manufacturer
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