(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

CAS NO.：70396-18-8
Empirical Formula: C13H24N2O5
Molecular Weight: 288.34
MDL number: MFCD22381612
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-26 20:01:30

What is (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid?

Description

Boc-Val-Ala-OH is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Properties of (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

Boiling point:	493.3±30.0 °C(Predicted)
Density	1.121±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	3.50±0.10(Predicted)
form	Solid
color	White to off-white

Safety information for (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

Computed Descriptors for (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

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