(S)-2-(Methoxydiphenylmethyl)pyrrolidine
- CAS NO.：118971-03-2
- Empirical Formula: C18H21NO
- Molecular Weight: 267.37
- MDL number: MFCD09750440
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:02
What is (S)-2-(Methoxydiphenylmethyl)pyrrolidine?
The Uses of (S)-2-(Methoxydiphenylmethyl)pyrrolidine
(S)-2-(Methoxydiphenylmethyl)pyrrolidine is a diphenylprolinol methyl ether, which can be used as a catalyst to synthesize:
- Enantioselective ketones via intermolecular asymmetric Michael addition of aldehydes to nonactivated enones.
- Stereoselective chiral bipyrazolidin-3-one derivatives by dipolar cycloaddition reaction of azomethine imines with α, β-unsaturated aldehydes.
- Enantioenriched spiro nitrogen heterocycles via asymmetric nucleophilic epoxidation of α-ylideneoxindole esters.
- Optically active secondary alcohols by asymmetric addition of Et2Zn to various aldehydes.
Properties of (S)-2-(Methoxydiphenylmethyl)pyrrolidine
| Boiling point: | 368.7±32.0 °C(Predicted) |
| Density | 1.070±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | soluble in Dichloromethane, Ethyl Acetate |
| pka | 10.09±0.10(Predicted) |
| form | Oil |
| color | Yellow |
Safety information for (S)-2-(Methoxydiphenylmethyl)pyrrolidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-2-(Methoxydiphenylmethyl)pyrrolidine
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![(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride](https://img.chemicalbook.in/CAS/20200401/GIF/CB62101664.gif)
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