RuPhos Pd G2
Synonym(s):2nd Generation RuPhos Precatalyst;Chloro(2-dicyclohexylphosphino-2′,6′-diisopropoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II);RuPhos-Pd-G2
- CAS NO.：1375325-68-0
- Empirical Formula: C42H53ClNO2PPd
- Molecular Weight: 776.73
- MDL number: MFCD20264899
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:16:00
What is RuPhos Pd G2?
The Uses of RuPhos Pd G2
RuPhos Pd G2 may be employed as precatalyst in the preparation of fluoro-substituted diazatetracenes and diazapentacenes, via Pd-catalyzed aryl amination reaction.
Reactions
Palladium precatalyst for fast Suzuki-Miyaura coupling reactions.
General Description
RuPhos Pd G2 is a second generation (G2) precatalyst containing a biphenyl-based ligand. Product participates in various palladium catalyzed cross-coupling reactions, C-C, C-N, and C-O bond formation reactions and Suzuki-Miyaura coupling reactions. It generates active Pd catalyst at room temperature in the presence of weak phosphate or carbonate bases.
Properties of RuPhos Pd G2
| Melting point: | 195-197°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Powder |
| color | white |
| CAS DataBase Reference | 1375325-68-0 |
Safety information for RuPhos Pd G2
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for RuPhos Pd G2
| InChIKey | HAGBKELACJTOCE-UHFFFAOYSA-N |
| SMILES | P(C1CCCCC1)(C1CCCCC1)(C1C=CC=CC=1C1C(=CC=CC=1OC(C)C)OC(C)C)[Pd+2]1(NC2=CC=CC=C2C2=CC=CC=[C-]12)[Cl-] |
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