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HomeProduct name listrubrofusarin

rubrofusarin

Synonym(s):5,6-Dihydroxy-8-methoxy-2-methyl-benzo[g]chromen-4-one;CID 72537;NSC258316

rubrofusarin Structural

What is rubrofusarin?

The Uses of rubrofusarin

Rubrofusarin is useful for treating chronic restraint stress-induced depressive symptoms.

What are the applications of Application

Rubrofusarin is an inhibitor of RNA Polymerase and Tyrosinase

Definition

ChEBI: A member of the class of benzochromenones that is benzo[g]chromen-4-one carrying two additional hydroxy substituents at positions 5 and 6 as well as methyl and methoxy substituents at positions 2 and 8 respectively. An orange polyketide pigmen that is a common intermediate in many different fungal biosynthetic pathways.

Biochem/physiol Actions

Rubrofusarin is an orange polyketide pigment produced by Fusarium graminearum and other fungal species that exhibit potent anti-cancer and anti-mycobacterial activities. Rubrofusarin is a mycotoxin that inhibits human DNA topoisomerase II-α.. Additionally, Rubrofusarin shows a significant anti-estrogenic activity.

Storage

+4°C

Properties of rubrofusarin

Melting point: 214℃ (benzene )
Boiling point: 438.7±45.0 °C(Predicted)
Density  1.432±0.06 g/cm3(Predicted)
storage temp.  -20°C
form  powder
pka 3.83±0.40(Predicted)
color  yellow to orange

Safety information for rubrofusarin

Computed Descriptors for rubrofusarin

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