RS 102221 HYDROCHLORIDE
Synonym(s):4-dione hydrochloride hydrate;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2
- CAS NO.：185376-97-0
- Empirical Formula: C27H31F3N4O7S
- Molecular Weight: 612.62
- MDL number: MFCD09971036
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is RS 102221 HYDROCHLORIDE?
The Uses of RS 102221 HYDROCHLORIDE
RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.
What are the applications of Application
RS 102221 hydrochloride is a selective SR-2C antagonist
Definition
ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.
Biological Activity
Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.
Properties of RS 102221 HYDROCHLORIDE
| Density | 1.45 |
| storage temp. | Store at RT |
| solubility | DMSO: ≥20mg/mL |
| form | powder |
| color | white |
Safety information for RS 102221 HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for RS 102221 HYDROCHLORIDE
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
![1,3,8-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE](https://img.chemicalbook.in/CAS/GIF/13625-39-3.gif)
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