(R,R)-2,3-Butanediol

Chemical properties

colourless or slightly brown liquid

The Uses of (R,R)-2,3-Butanediol

(2R,3R)-(-)-2,3-Butanediol is used as a chiral auxiliary, chiral ligand and building block. Cyclocondenses with ketones for (13)C NMR determination of optical purity. It is used in the resolution of carbonyl compounds in gas chromatography.

The Uses of (R,R)-2,3-Butanediol

C₂ symmetric chiral diol with versatile applications as a chiral auxiliary, building block, and chiral ligand. Cyclocondenses with ketones for ¹³C NMR determination of optical purity.

What are the applications of Application

(2R,3R)-(?)-2,3-Butanediol is a chiral synthetic intermediate

Definition

ChEBI: The (R,R) diastereoisomer of butane-2,3-diol.

General Description

(2R,3R)-(-)-2,3-Butanediol is a key building block in pharmaceutical industry.

Flammability and Explosibility

Not classified

Purification Methods

Purify it by fractional distillation. The bis-(4-nitrobenzoate) has m 141-142o and [] (-) or (+) 52o (c 4 CHCl3). [Ghirardelli & Lucas J Am Chem Soc 79 734 1957, Rubin et al. J Am Chem Soc 74 425 1952, Neish Can J Res 27 6 1949, Neish & Ledingham Can J Res 27 694 1949, Beilstein 1 IV 2524-2525.]