(R,R)-2,3-Butanediol
- CAS NO.：24347-58-8
- Empirical Formula: C4H10O2
- Molecular Weight: 90.12
- MDL number: MFCD00064267
- EINECS: 246-186-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-09 18:56:23
What is (R,R)-2,3-Butanediol?
Chemical properties
colourless or slightly brown liquid
The Uses of (R,R)-2,3-Butanediol
(2R,3R)-(-)-2,3-Butanediol is used as a chiral auxiliary, chiral ligand and building block. Cyclocondenses with ketones for (13)C NMR determination of optical purity. It is used in the resolution of carbonyl compounds in gas chromatography.
The Uses of (R,R)-2,3-Butanediol
C2 symmetric chiral diol with versatile applications as a chiral auxiliary, building block, and chiral ligand. Cyclocondenses with ketones for 13C NMR determination of optical purity.
What are the applications of Application
(2R,3R)-(?)-2,3-Butanediol is a chiral synthetic intermediate
Definition
ChEBI: The (R,R) diastereoisomer of butane-2,3-diol.
General Description
(2R,3R)-(-)-2,3-Butanediol is a key building block in pharmaceutical industry.
Flammability and Explosibility
Not classified
Purification Methods
Purify it by fractional distillation. The bis-(4-nitrobenzoate) has m 141-142o and [] (-) or (+) 52o (c 4 CHCl3). [Ghirardelli & Lucas J Am Chem Soc 79 734 1957, Rubin et al. J Am Chem Soc 74 425 1952, Neish Can J Res 27 6 1949, Neish & Ledingham Can J Res 27 694 1949, Beilstein 1 IV 2524-2525.]
Properties of (R,R)-2,3-Butanediol
| Melting point: | 16 °C |
| Boiling point: | 77.3-77.4 °C/10 mmHg (lit.) |
| alpha | -13 º (neat) |
| Density | 0.987 g/mL at 25 °C (lit.) |
| vapor pressure | 82.8Pa at 25℃ |
| refractive index | n |
| Flash point: | 185 °F |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| form | Liquid |
| pka | 14.67±0.20(Predicted) |
| color | Clear colorless |
| optical activity | [α]23/D 13.2°, neat |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| Merck | 14,1568 |
| BRN | 4290593 |
| Stability: | Stable. Hygroscopic, air sensitive. Incompatible with strong oxidizing agents, acid anhydrides, acid chlorides, chloroformates, reducing agents. Combustible. |
| CAS DataBase Reference | 24347-58-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,3-Butanediol, [R-(R*,R*)]-(24347-58-8) |
Safety information for (R,R)-2,3-Butanediol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for (R,R)-2,3-Butanediol
| InChIKey | OWBTYPJTUOEWEK-QWWZWVQMSA-N |
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