RQ-00311651
- CAS NO.：1257116-00-9
- Empirical Formula: C19H18F3N5O2
- Molecular Weight: 405.37
- Update Date: 2026-04-22 18:57:36
What is RQ-00311651?
Description
RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ～ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.
Properties of RQ-00311651
| Boiling point: | 655.8±55.0 °C(Predicted) |
| Density | 1.425±0.06 g/cm3(Predicted) |
| pka | 11.95±0.10(Predicted) |
Safety information for RQ-00311651
Computed Descriptors for RQ-00311651
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