Roxarsone

Synonym(s):2-Nitrophenol-4-arsonic acid;4-Hydroxy-3-nitrobenzenearsonic acid

CAS NO.：121-19-7
Empirical Formula: C6H6AsNO6
Molecular Weight: 263.04
MDL number: MFCD00007112
EINECS: 204-453-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-24 14:58:22

What is Roxarsone ?

Chemical properties

BEIGE-BROWN FINE CRYSTALLINE POWDER

The Uses of Roxarsone

antiinfective, preservative

The Uses of Roxarsone

4-Hydroxy-3-nitrophenylarsonic Acid is used as a feed additive for chicken to aid in the prevention of coccidiosis caused by E[imeria] tenella and E. necatrix.

The Uses of Roxarsone

Formerly in manufacture of arsphenamines; as reagent for zirconium.

What are the applications of Application

Roxarson is a feed additive for chicken to aid in the prevention of coccidiosis caused by E[imeria] tenella and E. necatrix.

Definition

ChEBI: An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.

General Description

Pale yellow crystals or light tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

May be sensitive to light and elevated temperatures on long-term storage. Roxarsone puffs up and deflagrates on heating. Incompatible with strong oxidizers and strong acids. Forms mono-, di-, and trisodium salts.

Hazard

Toxic by ingestion, highly toxic.

Fire Hazard

Flash point data are not available for Roxarsone ; however, Roxarsone is probably combustible.

Purification Methods

It crystallises from water and is used for the spectroscopic detection of Zn. [Beilstein 16 II 468, 16 III 1073, 16 IV 1188.]

Properties of Roxarsone

Melting point:	≥300 °C(lit.)
Boiling point:	537.3±60.0 °C(Predicted)
Density	2.02 g/cm3
storage temp.	0-6°C
solubility	insoluble in Ether
form	liquid
pka	3.51±0.10(Predicted)
color	Light yellow to Yellow
Water Solubility	<0.1 g/100 mL at 23 ºC
Merck	14,8273
BRN	1976533
Stability:	Hygroscopic
CAS DataBase Reference	121-19-7(CAS DataBase Reference)
EPA Substance Registry System	Roxarsone (121-19-7)

Safety information for Roxarsone

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.