Ropivacaine hydrochloride

The Uses of Ropivacaine hydrochloride

anesthetic

The Uses of Ropivacaine hydrochloride

2-Piperidinecarboxamide hydrochloride is a useful research chemical compound.

Definition

ChEBI: The anhydrous form of (S)-ropivacaine hydrochloride.

Description

Ropivacaine hydrochloride is an aminoamide local anesthetic drug.

Mechanism of action

Local anesthetics like ropivacaine block the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. Specifically, they block the sodium channel and decrease chances of depolarization and consequent action potentials. In general, the progression of anesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibers.

Side Effects

Most side effects relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur.Systemic exposure to excessive quantities of ropivacaine mainly result in central nervous system (CNS) and cardiovascular effects.