Ropivacaine hydrochloride
Synonym(s):(2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate;(S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate;Naropin hydrochloride monohydrate;Ropivacaine hydrochloride monohydrate
- CAS NO.：132112-35-7
- Empirical Formula: C17H26N2O.ClH.H2O
- Molecular Weight: 328.88
- MDL number: MFCD02102164
- EINECS: 663-286-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-28 19:59:05
What is Ropivacaine hydrochloride ?
Description
(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
The Uses of Ropivacaine hydrochloride
Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.
What are the applications of Application
Ropivacaine Hydrochloride Monohydrate is A reversible blockade of impulse propagation
Properties of Ropivacaine hydrochloride
| Melting point: | 267-269°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear |
| form | powder |
| color | white to off-white |
Safety information for Ropivacaine hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ropivacaine hydrochloride
| InChIKey | VSHFRHVKMYGBJL-CKUXDGONSA-N |
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