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HomeProduct name listrolapitant hydrochloride (anhydrous)

rolapitant hydrochloride (anhydrous)

rolapitant hydrochloride (anhydrous) Structural

What is rolapitant hydrochloride (anhydrous)?

The Uses of rolapitant hydrochloride (anhydrous)

Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.

Definition

ChEBI: Rolapitant hydrochloride (anhydrous) is a hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of the hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy. It has a role as an antiemetic and a neurokinin-1 receptor antagonist. It contains a rolapitant(1+).

Properties of rolapitant hydrochloride (anhydrous)

solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White

Safety information for rolapitant hydrochloride (anhydrous)

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for rolapitant hydrochloride (anhydrous)

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