Ro 314724
- CAS NO.：112105-54-1
- Empirical Formula: C19H35N3O6
- Molecular Weight: 401.5
- MDL number: MFCD00907191
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is Ro 314724?
Description
RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.
Properties of Ro 314724
| Density | 1.106±0.06 g/cm3(Predicted) |
| pka | 9.17±0.20(Predicted) |
Safety information for Ro 314724
Computed Descriptors for Ro 314724
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