RJR-2429 2HCL
- CAS NO.:91556-75-1
- Empirical Formula: C12H16N2.2ClH
- Molecular Weight: 261.194
- MDL number: MFCD03788206
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is RJR-2429 2HCL?
The Uses of RJR-2429 2HCL
RJR 2429 is a potent AChR agonist.
Biological Activity
Potent nAChR agonist that displays selectivity for α 4 β 2 (K i = 1 nM) and α 1 β γ δ subtypes (EC 50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC 50 = 2 nM) and inhibits ion flux in thalamic neurons (IC 50 = 154 nM). Also putative α 3 β 4 agonist that potentiates catecholamine release.
Properties of RJR-2429 2HCL
| Boiling point: | 295.6±15.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | H2O: 5 mg/mL |
| form | solid |
| pka | 9.41±0.40(Predicted) |
| color | white |
Safety information for RJR-2429 2HCL
Computed Descriptors for RJR-2429 2HCL
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