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HomeProduct name listRJR-2429 2HCL

RJR-2429 2HCL

RJR-2429 2HCL Structural

What is RJR-2429 2HCL?

The Uses of RJR-2429 2HCL

RJR 2429 is a potent AChR agonist.

Biological Activity

Potent nAChR agonist that displays selectivity for α 4 β 2 (K i = 1 nM) and α 1 β γ δ subtypes (EC 50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC 50 = 2 nM) and inhibits ion flux in thalamic neurons (IC 50 = 154 nM). Also putative α 3 β 4 agonist that potentiates catecholamine release.

Properties of RJR-2429 2HCL

Boiling point: 295.6±15.0 °C(Predicted)
Density  1.11±0.1 g/cm3(Predicted)
storage temp.  Desiccate at RT
solubility  H2O: 5 mg/mL
form  solid
pka 9.41±0.40(Predicted)
color  white

Safety information for RJR-2429 2HCL

Computed Descriptors for RJR-2429 2HCL

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