RHETSININE (Hydroxyevodiamine)

Description

This alkaloid was first obtained from Evodia rutecarpa Benth. & Hook and subsequently found in Xanthoxylum rhetsa D.C. It yields yellow-orange crystals for which a melting point of 192° C (dec.) has also been given in addition to that shown above. The hydrochloride forms yellow needles when crystallized from EtOH, m.p. 228-9°C (dec.); the picrate, yellow needles, m.p. 270-2°C (dec. ) and the methiodide, m.p. 220-1 ° C (dec.). Two of the nitrogen atoms are present in a carbolone residue, the third being in the N-methylaniline moiety.

References

Asahina, Ohta., J. Pharm. Soc., Japan, 530, 293 (1926)
Chatterjee, Bose, Ghosh., Tetrahedron, 7,257 (1959)
Gopinath, Govindachari, Rao., ibid, 8, 293 (1960)
Pachter, Sulol., J. Org. Chem., 25, 1680 (1960)