RHAPONTIN

Synonym(s):3,3′,5-Trihydroxy-4′-methoxystilbene 3-O-β-D-glucoside;NSC 43321;Rhaponticin;Rhapontin

CAS NO.：155-58-8
Empirical Formula: C21H24O9
Molecular Weight: 420.41
MDL number: MFCD00010117
EINECS: 205-845-0
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-22 14:50:28

What is RHAPONTIN?

Chemical properties

light beige powder

The Uses of RHAPONTIN

Rhapontin is a stilbene derivative found in Rheum. It is an inhibitor of Tyrosinase which is responsible for the molting process in insects, undesirable browning of fruits and vegetables, and coloring of skin, hair, and eyes in animals.

What are the applications of Application

Rhapontin is a growth inhibitor and apoptosis inducer

Definition

ChEBI: Trans-rhaponticin is a rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. It has a role as an anti-inflammatory agent, a plant metabolite, a neuroprotective agent, an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, an apoptosis inducer, an angiogenesis inhibitor, a hypoglycemic agent, an anti-allergic agent and an antilipemic drug.

Properties of RHAPONTIN

Melting point:	236-240 °C
Boiling point:	457.61°C (rough estimate)
alpha	D32 -59.5° (acetone)
Density	1.2828 (rough estimate)
refractive index	1.6230 (estimate)
storage temp.	2-8°C
solubility	Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
form	neat
form	Solid
pka	9.16±0.10(Predicted)
color	Brown
Water Solubility	slightly soluble in water
Merck	13,8258
Stability:	Hygroscopic