Rapacuronium
- CAS NO.：156137-99-4
- Empirical Formula: C37H61BrN2O4
- Molecular Weight: 677.81
- MDL number: MFCD00870871
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is Rapacuronium?
Description
Rapacuronium bromide was introduced in the US as a parenterally administered adjunct to general anesthesia during surgical procedures. It is a new steroidal derivative belonging to the same class as vecuronium bromide. This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking drug with a rapid onset and a short duration of action. With a relatively low potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for the polarizing succinylcholine with very short duration of action.
Originator
Akzo Nobel (Netherlands)
The Uses of Rapacuronium
Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia.
brand name
Raplon
Properties of Rapacuronium
| Melting point: | 184° |
| alpha | 20D -12.7° (c = 1.01 in CHCl3) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 125 mg/mL (184.42 mM) |
| form | Solid |
| color | Light yellow to yellow |
Safety information for Rapacuronium
Computed Descriptors for Rapacuronium
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