rac BHFF
Synonym(s):5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl) -2(3H)-benzofuranone, 5,7-Di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one
- CAS NO.：123557-91-5
- Empirical Formula: C17H21F3O3
- Molecular Weight: 330.34
- MDL number: MFCD03764148
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is rac BHFF?
The Uses of rac BHFF
rac BHFF is a positive allosteric modulator of GABAB receptors.
What are the applications of Application
rac BHFF is a GABAB receptor positive allosteric modulator
Biological Activity
Potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). Exhibits anxiolytic activity in vivo and is orally active.
Storage
Store at +4°C
Properties of rac BHFF
| Melting point: | 83 °C(Solv: heptane (142-82-5)) |
| Boiling point: | 322.1±42.0 °C(Predicted) |
| Density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | DMSO: ≥15mg/mL |
| form | powder |
| pka | 9.42±0.20(Predicted) |
| color | white to beige |
Safety information for rac BHFF
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for rac BHFF
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