(R)-Baclofen
- CAS NO.：69308-37-8
- Empirical Formula: C10H12ClNO2
- Molecular Weight: 213.66
- MDL number: MFCD01321057
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is (R)-Baclofen?
Chemical properties
White Solid
The Uses of (R)-Baclofen
(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
The Uses of (R)-Baclofen
R-Enantiomer of Baclofen. Specific GABA-B receptor agonist. Muscle relaxant (skeletal).
What are the applications of Application
R-(+)-Baclofen (free base) is a selective GABAB receptor agonist
Definition
ChEBI: Arbaclofen is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.
Biological Activity
More active enantiomer of ( RS )-Baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid) , a selective GABA B agonist.
Storage
Room temperature
Properties of (R)-Baclofen
| Melting point: | 171-174°C |
| Boiling point: | 364.3±32.0 °C(Predicted) |
| Density | 1.285±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| Water Solubility | Practically insoluble in water |
| solubility | Methanol (Slightly, Sonicated), Water (Slightly, Sonicated) |
| pka | 4.04±0.10(Predicted) |
| form | powder to crystaline |
| color | White to Almost white |
| CAS DataBase Reference | 69308-37-8(CAS DataBase Reference) |
Safety information for (R)-Baclofen
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for (R)-Baclofen
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![BACLOFEN (-), [BUTYL-4-3H(N)]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2301745.gif)
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