(R)-4-Chloro-3-hydroxybutyronitrile
- CAS NO.：84367-31-7
- Empirical Formula: C4H6ClNO
- Molecular Weight: 119.55
- MDL number: MFCD00273362
- EINECS: 624-620-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:35:40
What is (R)-4-Chloro-3-hydroxybutyronitrile?
Chemical properties
Colorless to pale yellow liquid
The Uses of (R)-4-Chloro-3-hydroxybutyronitrile
(R)-(+)-4-Chloro-3-hydroxybutyronitrile is a chiral reagent used in asymmetric catalysis in organic synthesis.
The Uses of (R)-4-Chloro-3-hydroxybutyronitrile
(-)-Carnitine and (-)-γ-amino-β-hydroxybutyric acid have been prepared using this synthon.
Properties of (R)-4-Chloro-3-hydroxybutyronitrile
| Boiling point: | 110 °C1 mm Hg(lit.) |
| alpha | 11 º (neat) |
| Density | 1.250 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| form | clear liquid |
| pka | 12.67±0.20(Predicted) |
| color | Colorless to Light yellow |
| optical activity | [α]25/D +11.0°, neat |
| BRN | 1700586 |
| CAS DataBase Reference | 84367-31-7(CAS DataBase Reference) |
Safety information for (R)-4-Chloro-3-hydroxybutyronitrile
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-4-Chloro-3-hydroxybutyronitrile
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