(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

Chemical properties

White solid

The Uses of (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in Pharmaceutical and industry applications.

The Uses of (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

Ligand employed in the asymmetic hydrogenation of ?-keto esters, 2-arylacrylates, aryl ketones , and other substrates.

Reactions

1. Chiral ligand for the asymmetric hydrogenation of β-keto esters.
2. Chiral ligand for enantioselective rhodium-catalyzed [2+2+2] carbocyclization reactions.
3. Chiral ligand for ruthenium catalyzed hydrogenation of (E)-β-(acylamino)acrylates to β-amino acids.
4. The Rhodium complex gives higher enantioselectivity for hydrogenation of (Z)-β-(acylamino)acrylates to β-amino acids.
5. Chiral ligand for copper-catalyzed asymmetric hydrosilylation of ketones.
6. Chiral ligand for asymmetric allylic substitution reactions using boronic acids as nucleophiles.
7. Gives useful selectivity in asymmetric Pauson-Khand-type cyclizations.