(R)-1-Boc-3-Hydroxypiperidine
Synonym(s):(R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
- CAS NO.：143900-43-0
- Empirical Formula: C10H19NO3
- Molecular Weight: 201.26
- MDL number: MFCD04115306
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is (R)-1-Boc-3-Hydroxypiperidine?
Chemical properties
White powder
The Uses of (R)-1-Boc-3-Hydroxypiperidine
(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.
Properties of (R)-1-Boc-3-Hydroxypiperidine
| Melting point: | 43-50 °C |
| Boiling point: | 292.3±33.0 °C(Predicted) |
| Density | 1.107±0.06 g/cm3(Predicted) |
| Flash point: | 104°C |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| form | Low Melting Solid |
| pka | 14.74±0.20(Predicted) |
| color | White to tan |
| optical activity | [α]/D 22±3°, c = 5 in methanol |
| CAS DataBase Reference | 143900-43-0(CAS DataBase Reference) |
Safety information for (R)-1-Boc-3-Hydroxypiperidine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for (R)-1-Boc-3-Hydroxypiperidine
| InChIKey | UIJXHKXIOCDSEB-MRVPVSSYSA-N |
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