Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]-
- CAS NO.：898562-99-7
- Empirical Formula: C26H19F3N4O
- Molecular Weight: 460.45
- Update Date: 2026-05-22 09:14:11
![Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]- Structural](https://img.chemicalbook.in/CAS/20210305/GIF/898562-99-7.gif)
What is Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]-?
Biological Activity
PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders[1].
References
[1]. Patrick Robert Verhoest, et al. Heteroaromatic quinoline compounds and their use as pde10 inhibitors. WO2006072828 A2 (Example 8)
Properties of Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]-
| Boiling point: | 564.4±50.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 31.25 mg/mL (67.87 mM; ultrasonic and warming and heat to 60°C) |
| pka | 4.08±0.10(Predicted) |
| form | Solid |
| color | Off-white to light yellow |
Safety information for Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]-
Computed Descriptors for Quinoline, 2-[[4-[4-(4-pyridinyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]phenoxy]methyl]-
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