QUAZINONE
- CAS NO.：70018-51-8
- Empirical Formula: C11H10ClN3O
- Molecular Weight: 235.67
- MDL number: MFCD00211176
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 22:16:43
What is QUAZINONE?
Description
Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM).
The Uses of QUAZINONE
Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties.
The Uses of QUAZINONE
Cardiotonic.
What are the applications of Application
Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties
References
1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties; J. Cardiovasc. Pharmacol., 6 511 2) Holck et al. (1984) Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties; J. Cardiovasc. Pharmacol. 6 520
Properties of QUAZINONE
| storage temp. | RT |
| solubility | ethanol: soluble1mg/mL |
| form | White to off-white solid. |
| color | white |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months |
Safety information for QUAZINONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for QUAZINONE
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